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What you are saying Tim is that no system is idiot-proof - and I can give
you plenty of examples of juniors getting the units wrong and
mis-interpreting lab results (once every 6 months, mysteriously correlating
with the medical and surgical rotations) long before SI units became
commonplace in hospital lab practice.

Drug results make more sense in SI units and it would be a step forward to
move away from the "we've always done it that way" solution to this problem.

Nick Miller
London

On 04/12/06, Reynolds Tim <[log in to unmask]> wrote:
>
>  But when juniors move from one hospital to another and the A&E dept
> ignore the units when writing down results, it is a problem. In fact, it
> is a systems problem that can be dealt with very simply by agreeing which
> units to use on a country-wide basis.
>
> You could conceive of an airline problem where a plane crashed someone
> striped a vital bolt by using UNF instead of BNF gauge threads. It would be
> inconceivable that that was not solved.
> And before you say that this could never happen, the Hubble space
> telescope has a mirror problem because someone specified a particular type
> of bolt in the grinder monitoring system, and the other type of bolt was
> used, resulting in the mirror being mis-ground. We have the same with drug
> measurement. Units are an arbitrary (albeit formalised arbitrary) method of
> recording something so that people agree - if they can't agree because they
> use different units and someone dies as a result, where does the problem
> lie: It lies with the disagreement over units - so the solution is obvious -
> agree on the same units. If you can't agree then there should be a decree
> from someone in power that the same units should be used for whatever
> mission critical system that needs to be fixed.
>
> So who cares whether we measure in mg/L, mg/dL, mmol/swimming pool or
> widgets/employee' Provided we all report in the same units the safety
> problem is solved...
>
>
> *************************************************************************************
> Prof. Tim Reynolds,
> Queen's Hospital,
> Belvedere Rd,
> Burton-on-Trent,
> Staffordshire,
> DE13 0RB
>
> work tel: 01283 511511 ext. 4035
> work fax: 01283 593064
> work email: [log in to unmask]
> home email: [log in to unmask]
>
> **************************************************************************************
> IMPORTANT: This email is intended for the use of the individual
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>
>   -----Original Message-----
> *From:* Clinical biochemistry discussion list [mailto:
> [log in to unmask]] *On Behalf Of *Nick Miller
> *Sent:* 04 December 2006 11:46
> *To:* [log in to unmask]
> *Subject:* Re: Consensus statement on reporting drugs and poisons
>
> Tim,
>
>  It's absurb to blame the choice of units for the failure of  A&E SHO's to
> familiarise themselves with the reference range for drugs or any other lab
> tests (unless the lab changed the units and reference ranges without telling
> anyone - which is unlikely).
>
> And yes, pharmaceuticals act and interact according to the molarity of
> their active components, so SI units are the appropriate choice for
> reporting their concentrations in body fluids.
>
>
> Nick Miller
> London
>
>  On 04/12/06, Reynolds Tim <[log in to unmask]> wrote:
>
> >  Having heard of a recent death due to paracetamol in a patient because
> > the lab reported in mmol/L and the A&E dept interpreted in mg/L and
> > discharged the patient, I don't think it matters what we report in provided
> > everyone does the same. In this situation we have a proven cause of death
> > that could be prevented if everyone agreed to do the same thing - the sort
> > of problem that the safety experts always say we should be following
> > airline-type procedures to prevent. Since drugs are measured in mg / liter
> > it seems reasonable to report concentration in mg/L but what does it matter!
> >
> >
> > Perhaps we should decide to report in ounces/gallon - then at least
> > everyone will be united in hating the 'new' units.
> >
> >
> > TIM
> >
> >
> >
> > *************************************************************************************
> > Prof. Tim Reynolds,
> > Queen's Hospital,
> > Belvedere Rd,
> > Burton-on-Trent,
> > Staffordshire,
> > DE13 0RB
> >
> > work tel: 01283 511511 ext. 4035
> > work fax: 01283 593064
> > work email: [log in to unmask]
> > home email: [log in to unmask]
> >
> > **************************************************************************************
> > IMPORTANT: This email is intended for the use of the individual
> > addressee(s)named above and may contain information that is confidential
> > privileged or unsuitable for overly sensitive persons with low self-esteem,
> > no sense of humour or irrational religious beliefs. If you are not the
> > intended recipient, any dissemination, distribution or copying of this email
> > is not authorized (either explicitly or implicitly) and constitutes an
> > irritating social faux pas. Unless the word absquatulation has been used in
> > its correct context somewhere other than in this warning, it does not have
> > any legal or grammatical use and may be ignored. No animals were harmed in
> > the transmission of this email, though the kelpie next door is living on
> > borrowed time, let me tell you. Those of you with an overwhelming fear of
> > the unknown will be gratified to learn there is no hidden message revealed
> > by reading this backwards, so just ignore that Alert Notice from Macroshaft.
> > However, by pouring a complete circle of salt around yourself and your
> > computer you can ensure that no harm befalls you and your pets. If you have
> > received this eMail in error, please add some nutmeg and egg whites, whisk,
> > and place in a warm oven for 40 minutes.
> >
> >
> >   -----Original Message-----
> > *From:* Clinical biochemistry discussion list [mailto:[log in to unmask]]
> > *On Behalf Of *Colley, Michael
> > *Sent:* 04 December 2006 09:46
> > *To:* [log in to unmask]
> > *Subject:* Re: Consensus statement on reporting drugs and poisons
> >
> > As activity is molar, I'd go for molar.  It's the American Drug
> > Companies and the Pharmacists who're the main perpetuators of mass measure.
> >
> >
> > Mrs. X is just as unlikely to understand 5mg.  She understands that she
> > needs one tablet of A and another of B.
> > After all, a 5mg tablet of A weighs a heck of a lot more than 5mg!
> >
> > Perhaps, using the arguments for mass we should be going back to mg/dL
> > for glusoce and all other analytes including sodium and potassium.
> >
> > Michael (it's Monday morning!!)#
> >
> > -----Original Message-----
> > From: Williams David G (RLN) City Hospitals Sunderland - Clinical
> > Scientist [ mailto:[log in to unmask]<[log in to unmask]>
> > ]
> > Sent: 01 December 2006 14:13
> > To: [log in to unmask]
> > Subject: Re: Consensus statement on reporting drugs and poisons
> >
> >
> > Good news then. While I appreciate some of the purists among us may pine
> > for
> > the mole, I doubt if the likely confusion on the wards and for patients
> > will
> > do us any good at all.
> >
> > (Cut to GP surgery "Right then Mrs X, I'm going to prescribe 22.56 mmol
> > of Y
> > and 347 umol of Z for you to be taken twice daily after meals")
> >
> > David G Williams
> >
> > -----Original Message-----
> > From: Julian Barth [mailto:[log in to unmask]
> > <[log in to unmask]>]
> > Sent: 01 December 2006 13:44
> > To: [log in to unmask]
> > Subject: Consensus statement on reporting drugs and poisons
> >
> > Dear Colleagues
> >
> > I have to date had no real responses regading the proprosal that all
> > clinical laboratories in the UK report drugs and poisons in MASS SI
> > units.  I am very pleased to inform you that the Scottish Senior
> > Clinical Biochemists Group have recently agreed that all laboratoies in
> > Scotland will be shanging to mass units.
> >
> > I assume that the total silence means that there are no objections to a
> > change in England too, so can we have a discussion about time lines for
> > a change over?
> >
> > Yours hopefully
> > Julian
> >
> > Julian H Barth MD FRCP FRCPath
> > Consultant in Chemical Pathology & Metabolic Medicine
> > Department of Clinical Biochemistry & Immunology
> > Leeds General Infirmary
> > Leeds LS1 3EX
> >
> > tel 0113 392 3416
> > fax 0113 392 5174
> >
> > Editor-in-Chief, Annals of Clinical Biochemistry,
> > http://mc.manuscriptcentral.com/acb
> >
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