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Hi Stephan, >we would like to build our own fp-cit and ß-cit spect template. Could anybody give us a hint to realize that? Is it possible to use composite images for this template? Absolutely. Searching for "making template" in the archives (http://www.jiscmail.ac.uk/cgi-bin/wa.exe?S1=spm) yields plenty of references. The principle is to co-register the images in the modality you want a template for with something else for which there already is an MNI/ICBM152 space template (usually T1 MRI), normalise e.g. T1 to T1, drag coregistered new modality images along, check very carefully indeed, and create a "soft mean" (search for "Template" and "John Ashburner" in sender). Composite (integrated/add?) images can be used and are often a good idea, particularly if parametric images lack anatomical features. Obviously having a single slice template does not make much sense but I trust that's just a typo in your subject line. Good luck, Alexander ------------------------------- Dr Alexander Hammers, MD PhD MRC Clinician Scientist Fellow Honorary Clinical Lecturer Clinical Sciences Centre Room 243, MRC Cyclotron Building Faculty of Medicine, Imperial College London Hammersmith Hospital, DuCane Road, London W12 0NN and Honorary Lecturer in Neurology Department of Clinical and Experimental Epilepsy National Hospital for Neurology and Neurosurgery/ Institute of Neurology, UCL 33 Queen Square, London WC1N 3BG Telephone +44-(0)20-8383-3162 (ext./direct line -3704 or -2651) Fax +44-(0)20-8383-1783 /-2029 Email [log in to unmask], [log in to unmask]