Here are the updated 'Makefile' and 'spm_platform.m' for Matlab on 64bit Linux. 'Makefile': ----------- Mex-files on Matlab for 64bit linux getthe extension mexa64. So I added this to the architecture list: Linux.a64: make all SUF=mexa64 CC="gcc -O3 -funroll-loops -fPIC -march=x86-64" MEX="mex COPTIMFLAGS='-O3 -funroll-loops -fPIC -march=x86-64'" The '-fPIC' option is nexessary to allow the linking proces to complete. '-march=x86-64' provides generic optimisations for both Opteron and 64bit Xeon. If the code is running on a 64bit Xeon you can change '-march=x86-64' to '-march=nocona', when running on an Opteron, change it to '-march=opteron'. This might give you a performance boost. I added his to 'clean' details: clean.Linux.a64: make clean SUF=mexa64 and this to the 'messages' verb.mexa64: @ echo "_____________________________________________________________" @ echo "" @ echo "Linux compilation (Matlab 7.x) - using gcc for x86-64" @ echo "_____________________________________________________________" @ echo "" To build the mex-files, you go to the spm2 directory and do a 'make Linux.a64'. If you run into troubles, I can provide binaries for Opteron, Xeon and generic 'x86-64'. 'spm_platform.m': ----------------- Matlab for 64bit Linux identifies itself as 'GLNXA64' as opposed to 'GLNX86'. It has the same 'endian-ness' as GLNX86, so I added this to the 'PDefs' cell list: 'GLNXA64', 'unx', 0;... and added 'GLNXA64' to the list of other unix platforms at the font configuration. My system configuration: dual opteron 242 on a Tyan Tiger K8W Gentoo Linux for amd64 (also runs on Xeon with EM64T) Matlab 7.0.1.24704 (R14) Service Pack 1 for AMD64 gcc 3.4.3 glibc 2.3.4 -- Wouter Depuydt KUL - Neurofysiologie Herestraat 49, bus 801 B-3000 Leuven Tel. +32 (0)16 347112 Fax. +32 (0)16 345993 email [log in to unmask]