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Dear SPMasters : After analysis of 5 subjects with one scan in rest and one scan in minor seizure attack, we use pair t test with F contrast using SPM2. There were some clusters (size 59,56,54 for 3 largest cluster) when p=0.001, but when setting with FDR=0.05, there were no voxels declared active. Because the attacks are minor in clinical observation with only some limb movement, is this SPM(t) with uncorrected =0.001 give us some significance ? Or we should take this study as negative finding because FDR=0.05 show nothing ? Thanks Very much ! ChenChang Shih Taiwan