Hi, I'm trying to use a script to get the maximum T value from a mask I created in SPM2. The mask is basically a binary mask multiplied by a spmT image. Using a script, I am able to get the maximum T value and I'm also able to get at what coordinates in the matrix this T value occurrs, but I'm not sure how to go from the matrix coordinates into MNI coordinates, which is what I really want to know. Any help on this matter would be appreciated. See below for the script. Thank you. -Saul %Subjects list sub_list = str2mat('sub1','sub2','sub3'); %Directory where subjects are located working_dir = '/study_dir/'; %Directory where mask is located within subjects dir mask_dir = 'labels/'; %text file containing .img mask inputfile = 'ROIs.txt'; num_sub = size(sub_list,1); fid=fopen(inputfile); c=0; masks=[]; while 1 line = fgetl(fid); if ~isstr(line), break, end if c==0 masks=line; c=1; else masks=str2mat(masks,line); end end fclose(fid); [nummasks,temp]=size(masks); fid = fopen('T_values.txt','w'); for i=1:num_sub cur_sub = deblank(sub_list(i,:)); fprintf(fid,['Subject: ',cur_sub,'\n']); for j=1:nummasks highT = 0; x_coord = 0; y_coord = 0; z_coord = 0; mask_name = masks(j,:); m_num = strfind(mask_name,'.'); mask_label = masks(j,1:m_num-1); mask = spm_read_vols(spm_vol([working_dir,cur_sub,'/',mask_dir,mask_name])); for x=1:size(mask,1) for y=1:size(mask,2) for z=1:size(mask,3) if mask(x,y,z) > highT highT = mask(x,y,z); x_coord = x; y_coord = y; z_coord = z; end end end end fprintf(fid,[mask_label,': highest T: ',num2str(highT),' (',num2str(x_coord),',',num2str(y_coord),',',num2str(z_coord),')','\n']); end end fclose(fid);