Dear SPM List,

 

I am having a situation in which our functional images appear to be getting deformed in the normalization process using SPM2 (but not SPM99).  We have collected coronal images in which the frontal and occipital regions are not fully covered.  The raw images look fine, but during the normalization stage, it appears that for some (but not all) subjects, the images become very distorted.  For example, it appears that the brainstem is coming up out of the lower left quadrant on the coronal view, and the image in the axial view is barely recognizable and appears to be tilted.  When we take that same subject and normalize the data in SPM99, all the images look fine and there are no apparent problems with the data.   Has anyone else run into this issue or have any idea for a fix in terms of processing out data in SPM2?  What might cause there to be such a difference in normalization of images between SPM99 and SPM2 and why does this "deformation" only happen for some subjects in SPM2 but not all?

 

Any information/advice would be greatly appreciated!

 

Thank you.

Eve

 

 

Eve M. Valera, Ph.D.
Department of Psychiatry
Instructor, Harvard Medical School
Assistant in Research, Massachusetts General Hospital
617-724-0307 (office)
617-726-4078 (fax)

 

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