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Dear all,
Alex Hammers has pointed out to me that the tissue probability maps (in the 
tpm directory) released with SPM5b could be in better registration with the 
data of SPM2.  This is just to warn you that a slightly different set of 
tissue probability maps will be released in a forthcoming update to SPM5b.  
The same original data will be used - but it will simply be better registered 
with the older data.

If you plan to continue a study with the current set, then please make a 
backup copy of them, as downloading the updates is likely to over-write the 
current versions.

The data in the tpm directory is used by the Segment button of SPM5b, so if 
you plan to continue using renamed versions of the current tissue probability 
maps, then you will need to change the Spatial->Segment->Custom->Tissue 
probability maps setting in order to use them.  This can also be done by 
changing spm_defaults.m at around line 24, to something like:

defaults.preproc.tpm     = char(...
    fullfile(spm('Dir'),'tpm','old_grey.nii'),...
    fullfile(spm('Dir'),'tpm','old_white.nii'),...
    fullfile(spm('Dir'),'tpm','old_csf.nii')); % Prior probability maps

Best regards,
-John