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Dear Mitra, There should be no memory problem for that amount of data on the Linux system. Anyway, please try: 1) type ulimit before running Matlab on a terminal 2) check your swap file if it is less than 2 GB. Cheers, Witaya Sungkarat >Hi, >I am trying to do "Re-alignment" for one subject with 8 runs, each with 160 scans.Ther are 64 * 64 * 38 voxels in each scan. I am running SPM2 on Matlab 6.5 in Linux. Everytime I run, Matlab crashes. >I have 1GB RAM. I have 15GB of free space in my system. >Can you please help me how to resolve it. > >Thanks. >Mithra. >