Dear all, I noticed a wide variation in the global intensity of my (partial brain) epi volumes. I understand that there is some adjustment for this in SPM, but I was wondering at which stage does it take place and how exactly does it work. Thank you, Martin Martin Zalesak, M.Sc. PhD Candidate in Medical Engineering Harvard-MIT Division of Health Sciences and Technology Admissions Building, Rm. # 347 McLean Hospital 115 Mill St. Belmont, MA 02478 Phone: (617) 855-2961 Fax: (617) 855-2985 -------------------------------- Confidentiality notice: Any information, including protected health information (PHI), transmitted in this email is intended only for the person or entity to which it is addressed and may contain information that is privileged, confidential and or exempt from disclosure under applicable Federal or State law. Any review, retransmission, dissemination or other use of or taking of any action in reliance upon, protected health information (PHI) by persons or entities other than the intended recipient is prohibited. If you received this email in error, please contact the sender and delete the material from any computer.