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PhD Research Programme
Date available: Dec 2005


Clinical Pharmacology and Discovery Medicine at GlaxoSmithKline is committed to encourage the inclusion of paediatric considerations in GSK drug development programmes. On behalf of the coordinator of the GSK paediatric network I would like to inform you of the following opportunity:

A Fellowship Scheme has been established to foster closer interaction between clinical researchers and industry. A candidate for this fellowship is being sought for a collaboration in Pharmacometrics between the University of Leiden, The Netherlands and GlaxoSmithKline R&D.

New medicinal products with appropriate dosing recommendation should be made available to the paediatric population. However, developmental and intrinsic biological differences may or may not yield sub-populations for which a different dosing regimen is required. This fellowship involves exploring the utility of PK and PKPD modelling strategies for the evaluation of treatment effect in children. The extrapolation of data from one population to another and the analysis of treatment response in sub-populations will be the focus of this research programme.

The candidate will use a variety of modelling tools during the fellowship including NONMEM, WinBUGS and mathematical and statistical packages such as R / SPLUS. The candidate should hold a degree in Medicine, Pharmaceutical Sciences, Biostatistics, Bioengineering or a related field. Computer programming skills and some experience in the area of modelling are highly desirable. The successful candidate will spend time working at both the University of Leiden and GlaxoSmithKline R&D, UK. Excellent communication, interpersonal, and organisational skills are essential.


For further information please contact: Dr Oscar Della Pasqua ([log in to unmask])

Interested candidates should send their CV by e-mail Dr Oscar Della Pasqua by October 17th 2005.

Thank you for your interest.

Oscar Della Pasqua
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