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Dear All

Blood gas analysers measure pH and PCO2 using specific electrodes and calculate actual bicarbonate using various algorithms (based on Henderson Hasselbalch equation). It is unclear to me how the calculation of actual bicarbonate varies during acute vs chronic vs mixed acid base disturbances, if it is based on the Henderson equation only? Also can manufacturer's have built in software to provide an interpretation guide for a given set of blood gas readings, or is this considered too risky by them?

thanks

Mohammad




Dr. M A Al-Jubouri
Consultant Chemical Pathologist
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