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Some positive findings in new study on cocaine exposed children Public release date: 26-May-2004 Contact: George Stamatis [log in to unmask] 216-368-3635 Case Western Reserve University http://www.cwru.edu/ Some positive findings in new study on cocaine exposed children Exposure not associated with lower full scale IQ A study in the May 26 issue of the Journal of the American Medical Association (JAMA) suggests that prenatal cocaine exposure was not associated with lower full scale IQ scores, or verbal or performance IQ scores at age 4 years. However, the study also fo und that prenatal cocaine exposure was associated with specific cognitive impairments and a lower likelihood of an above average IQ, but that home environments could make a difference for better outcomes for some children. "Cocaine readily crosses the placental and fetal brain barriers and has a direct effect on the developing fetal brain ..." the authors provide as background information in the article. The authors add that "a number of methodologically sound studies have fo und a relationship between fetal cocaine exposure and negative child developmental outcomes in the first years of life, although others have not." In this study, Lynn T. Singer, Ph.D., from the Case Western Reserve University School of Medicine, and colleagues assessed the effects of prenatal cocaine exposure and the quality of the caregiving environment on cognitive outcomes. The participants inclu ded 376 children (190 cocaine-exposed and 186 non-exposed) from a high-risk population who were enrolled in a longitudinal study from birth (September 1994 June 1996). They were screened for drug exposure as infants, assessed at 6, 12 and 24 months of age and then tested at 4 years old for cognitive developments. The researchers found that prenatal cocaine exposure was not related to lower full-scale IQ scores (cocaine exposed 80.7 vs. nonexposed 82.9), summary verbal (cocaine exposed 79.9 vs. nonexposed 81.9) or performance IQ measures (cocaine exposed 85.5 vs. n onexposed 87.5) at age 4 years. "However, there were specific effects of prenatal cocaine exposure on several subscales, with cocaine-exposed children having lower information, arithmetic, and object assembly scores than nonexposed children," the research ers report. "Prenatal cocaine exposure was also associated with a lower likelihood of achievement of IQ above normative means." The researchers continue, "Comparisons indicated that cocaine-exposed children in foster or adoptive care lived in more stimulating home environments and their caregivers had better vocabulary scores than those of cocaine-exposed children in biological ma ternal or relative care and nonexposed children. In addition, cocaine-exposed children in foster or adoptive care had verbal, performance, and full-scale IQs equivalent to nonexposed children, while cocaine-exposed children in biological maternal or relat ive care had lower full-scale and performance IQ scores than nonexposed children, despite the fact that children in foster or adoptive care had twice the severity of cocaine exposure as measured by maternal report of the average numbers of 'rocks' of coca ine used weekly over the pregnancy. Moreover, the duration of placement in foster or adoptive care was positively related to full-scale IQ," the authors note. "These findings indicate that prenatal cocaine exposure is associated with an increased risk for specific cognitive impairments and a lower likelihood of above average IQ at 4 years of age. In addition, our findings underscore the beneficial effects of en vironmental intervention in the prevention of mental retardation for cocaine-exposed children. Drug treatment and education for this population of pregnant women, along with intensive intervention for their offspring, are essential to help maximize the fu ture well-being of these families," the authors conclude. Singer is also affiliated with MetroHealth Medical Center and University Hospitals of Cleveland. Rowdy Yates Senior Research Fellow Scottish Addiction Studies Sociology, Social Policy & Criminology Section Department of Applied Social Science University of Stirling Tel: +44(0)1786 - 467737 -- The University of Stirling is a university established in Scotland by charter at Stirling, FK9 4LA. Privileged/Confidential Information may be contained in this message. If you are not the addressee indicated in this message (or responsible for delivery of the message to such person), you may not disclose, copy or deliver this message to anyone and any action taken or omitted to be taken in reliance on it, is prohibited and may be unlawful. In such case, you should destroy this message and kindly notify the sender by reply email. Please advise immediately if you or your employer do not consent to Internet email for messages of this kind.