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Andrea and Steve,

Many thanks to for your suggestions. Íve made some tests with
siena_flow2tal (it took me a while to figure out that the script needs
some of the output from SIENA first) and now I get a threshold number and
a  *_FLOW_DIL and *_FLOW_TO_TAL images that I dońt know how to interpret.

I understand that a posterior voxel-wise analysis is a way to go but I was
thinking of a way to segment directly into ROÍs the
IM1_HALFWAYTO_IM2_RENDER output from SIENA??

On the other hand, the solution of J Chen is really neat: measuring the
atrophy in mm of cortical thickness change. That́s a much more practical
result and easy to interpret for a clinician like me. The problem is how
to get those numbers from SIENA output??

Does the script SIENA_FLOW2TAL include anything to do that?

Many thanks in advance!

Santiago

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 `·.¸¸.·´¯`·.¸.·´¯`·...¸><((((º>`·.¸¸.·´¯`·.¸.·´¯`·...¸><((((º>`·.¸¸.·´
Santiago Reig,  PhD.
   Gregorio Maranon Hospital,  Universidad Complutense de Madrid
   Experimental Surgery and Medicine Lab
   Dr. Esquerdo 46,  28007 Madrid, SPAIN
               Fax#  34 91 426 5108, Ph#  34 91 426 5067
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