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DJ time series analysis requires time series - all our functional tools work on 4D files. It seems that you've been trying to run it on a single 3D volume: >Melodic Version 2.0 > >Melodic results will be in /home/norm_volumes_1/nepi_vol_0002.ica > >Reading data file filtered_func_data ... done >Create mask ... done >Excluding voxels with constant value >Data size : 1 x 510340 You will need to create a 4d file first (avwmerge -t does this). If the file should have been 4D already, check the header information (avwhd) to see why it appears as a 3d volume ta c