Hello, I would like to set up a repeated measures 2x2 anova at the second level and examine the interaction. I have two groups of subjects (group 1 and 2) and each subject did 2 tasks (task A and B). The repeated measure would be the tasks (2 levels). I would like to ask the question: are there any task by group interactions ? I have set up things as described below and I have a few questions. I already have the COPE images for every subjects and task. I was thinking of setting up the second level analysis as follows (with smaller number of subjects for simplification). Each row represents a COPE image from one subject. group EV1 EV2 EV3 EV4 group_1_task_A_subj1 1 1 1 1 1 group_1_task_A_subj2 1 1 1 1 1 group_1_task_A_subj3 1 1 1 1 1 group_1_task_A_subj4 1 1 1 1 1 group_2_task_A_subj1 2 1 -1 -1 1 group_2_task_A_subj2 2 1 -1 -1 1 group_2_task_A_subj3 2 1 -1 -1 1 group_1_task_B_subj1 1 -1 1 -1 1 group_1_task_B_subj2 1 -1 1 -1 1 group_1_task_B_subj3 1 -1 1 -1 1 group_1_task_B_subj4 1 -1 1 -1 1 group_2_task_B_subj1 2 -1 -1 1 1 group_2_task_B_subj2 2 -1 -1 1 1 group_2_task_B_subj3 2 -1 -1 1 1 EV1 models task, EV2 models effects of group membership, EV3 the group x task interaction, and EV4 is the grand mean. The contrasts that I am thinking of implementing are as follows: 1 2 3 4 C1 1 0 0 0 C2 0 1 0 0 C3 0 0 1 0 and the F-tests are (with their interpretation) F1 F2 F3 C1 on off off - main effect of task C2 off on off - main effect of group C3 off off on - interaction between the two factors Question: is the repeated measures factor (task) the same as considering this variable as fixed and the other factor (group) as random ? I believe the F-tests above will not give me the exact test that I want but I am not sure. Thanks in advance, Arun