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Hi I'm having some problems registering my functional data onto a highres image of an individual subject's brain. My functional data is in the form of 24 obliquely oriented slices mainly covering the occipital area (it's a vision study). The clusters of activation seem to 'flame out' from the brain in some areas, into 'space' by a few millimetres. This problem seems to be worse in occipital areas and not so bad in parietal areas. I have an idea that occipital areas are subject to more distortion than other areas - is this true? To register my functional to a highres with flirt i did a 7 parameter global rescale transformation from my 24 slice functional data to a 120 slice EPI (slices at the same angle as the functional) and another 7 param global rescale to my individual highres structural. is there anything you could advise i do to improve my registration? many thanks for your time, Jane Aspell