PSI is holding an introductory course in Pharmacokinetics in Reading, UK on February 9-10, 2005 in association with Simcyp Limited. The course gives an introduction to aspects of the fate of drugs in the body in the context of drug discovery, development and therapeutic usage. A workshop component will complement the theoretical considerations. This will provide experience in solving numerical problems relating the time course of drugs and their metabolites in the body to the development of rational dosage guidelines. The course presenters are: Geoff Tucker, Professor of Clinical Pharmacology, University of Sheffield & Chairman, Simcyp Limited Amin Rostami - Hodjegan, Senior Lecturer in Pharmacokinetics, University of Sheffield & Director of Scientific Development, Simcyp Limited Applications are welcomed from statisticians and others who are interested in learning about this area of drug development, but all delegates must be members of PSI in order to attend. If you are not a PSI member and wish to attend the course, you must apply for membership of PSI and this must be approved before the course takes place. PSI application forms are available at www.psiweb.org, from whom an application form for the course and further details are also available. The course cost is £710 ex VAT. The closing date for all course applications is 9 January 2005. Please respond via the course link on the PSI website: www.psiweb.org only.