Imperial College London
Faculty of Medicine
Division of Primary Care and Population Health Sciences
St Mary's Campus, Paddington
SHORT COURSE: Introduction to Genetic Epidemiology
Thursday & Friday, 2nd & 3rd September 2004
This course provides an introduction to the methods used to analyse genetic epidemiology data in order to to assess the role of genes in causing disease, and to locate and characterize the genes involved. The course assumes a good grasp of basic statistics including likelihood-based estimation. No background in genetics is required, but familiarity with the basic genetics terms would be helpful. Our emphasis is on the principles of data analysis and study design rather than on the details of particular computational implementations.
Summary of course content:
* Introduction to some relevant genetics
* Segregation analysis
* Quantitative traits analysis
* Parametric linkage analysis (pedigree analysis)
* Non-parametric linkage analysis (e.g. affected sib-pairs)
* Association studies: case-control data
* Association studies: family data (e.g. TDT)
There will be extensive practical sessions in addition to lectures. Some of these will use the R statistical package, freely available from www.r-project.org An introduction to R will be included in the course.
Course Instructors: Professor David Balding and Dr John Whittaker, Imperial College London, Dr Cathryn Lewis, Kings College London.
Course Fee (inc. lunch): £400 (industry) £300 (academic, inc non-profit organisations) £200 (Imperial Staff and students)
Further details from: Wolfson Conference Centre
Imperial College School of Medicine
Hammersmith Hospital
Du Cane Road
London W12 0NN
Tel: +44 (0)20 8383 3117/3227/3245
Email: [log in to unmask]
