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Dear All, I am writing about the assocation of uterine fibroids and infertility and was using the 9 criteria described by Sackett et al in Clinical Epidemiology as the basis for the discussion. Does any one know if these have been further developed or written about in other places. That would be most useful. Here are the nine criteria for causality that I am using: Is there experimental evidence from human studies? Is the association strong? Is the association consistent from study to study? Is the temporal relationship correct? Is there a dose-response relationship? Does the association make epidemiological sense? Does the association make biological sense? Is the association specific? Is the association analogous to a previously proven causal association? Professor Cindy Farquhar Postgraduate Professor of Obstetrics and Gynaecology Department of Obstetrics and Gynaecology University of Auckland National Women's Hospital +64 9 6309943 ext 4092 (secretary) Direct Dial +64 9 6236848 Fax +64 9 6309858 -