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Dear Chain-ers, Several of us here have experience of the uncertainties of recruitment of subjects via general practices (family health clinics) onto research studies. The body of knowledge on factors influencing the 'success' or 'failure' of recruitment seems rather fragmented. I would be grateful for references to relevant explanatory research. There are several aspects of this: 1) What attracts GPs (family doctors / clinicians) to take part in multi-site studies? 2) What discourages them? 3) What retains GPs on studies? (this question can be interpreted as 'What influences whether they continue to follow the study and recruitment procedures', thereby attempting to exclude factors beyond GPs' control). 4) Conversely to no. 3, what study-related factors lead GPs to drop out of trials? All references, hints and pointers gratefully received. Thank you, Roy Marsh Research Facilitator Suffolk and Norfolk Primary Care Research Network (SuNet) School of Medicine, Health Policy and Practice University of East Anglia Norwich NR4 7TJ Tel. 01603 593746, Fax 593752