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We are analyzing data from a bloc design fMRI study (2 condtitions A,B and baseline C). We had 13 subjects. We showed the stimuli as [C A B C A B C A B] for 7 subjects and [C B A C B A C B A] for the other 6 subjects. Contrasts at the first level analysis were computed as follows: Con_0003.img was computed as A-C for both subject specification [-1 1 0] for 7 subjects and [-1 0 1] for the other 6 subjects. Con_0004.img was computed as B-C for both subject specification [-1 0 1] for 7 subjects and [-1 1 0] for the other 6 subjects. Con_0005.img was computed as A-B for both subject specification [ 0 1 -1] for 7 subjects and [0 -1 1] for the other 6 subjects. We are interested in the contrasts: (A-C)>(B-C) So we do the contrasts at the second level analysis as follows: 1. We select 13 Con_0003.img files of all the subjects and then 13 Con_0004.img files for all the subjects. 2. We specify the "group? " input as 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 Our question is to compute the (A-C)>(B-C) what should we contrast specify? Is it [ 1 -1 0] ? --------------------------------------------------------------- $B;38}Bg3XBg3X1! (B $BM}9)3X8&5f2J (B $BGn;N8e4|2]Dx#2G/ (B $B3k!!@9 (B Yamaguchi University Ge Sheng [log in to unmask]