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Thanks Paul and other responders So far I have reassuring replies like yours and other replies that advise exercising caution. The main issue is the lack of a commercial control at these low levels that one can use daily to report such low levels with some confidence. Some of you have used inhouse pooled sera for this purpose despite obvious reservations. What triggered this is a regional cardiologists risk stratification tool that gives various scores (1, 2, 3 and 4) for TnT levels of 0.04 -0.06, 0.07 - 0.09, 0.10 - 0.19 and > 0.2 ug/L respectively. The tool also gives scores for clinical indicators (such as age, smoking, hypertension, DM, dyslipidaemia, LV dysfunction and ECG findings). A patient accumulating score > 6 is labelled as very high risk, 3 - 6 High risk and < 3 Low risk. Our local cardiologist couldn't say whether this scoring system is evidence based or best guess based. Kind regards Mohammad --- Paul Collinson <[log in to unmask]> wrote: > In message > <[log in to unmask]>, > Mohammad > Al-Jubouri <[log in to unmask]> writes > > > Depends on your precision profile. The assay is > precise down to at least > 0.05 (and 0.013 in our hands). All positive results > mean cardiac damage > but not always AMI > > > >Dear elecsys 2010 users > > > >Is it safe to report TnT levels of 0.03 - 0.09 ug/L > on > >this analyser? What sort of quality control at > these > >low levels people use? NEQAS has only distributed > few > >samples with TnT < 0.1 ug/L. > > > >Thanks > > > >Mohammad > > > >===== > >Dr. M A Al-Jubouri > >Consultant Chemical Pathologist > > > >________________________________________________________________________ > >Want to chat instantly with your online friends? > Get the FREE Yahoo! > >Messenger http://uk.messenger.yahoo.com/ > > > >------ACB discussion List Information-------- > >This is an open discussion list for the academic > and clinical > >community working in clinical biochemistry. > >Please note, archived messages are public and can > be viewed > >via the internet. Views expressed are those of the > individual and > >they are responsible for all message content. > > > >ACB Web Site > >http://www.acb.org.uk > >List Archives > >http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html > >List Instructions (How to leave etc.) > >http://www.jiscmail.ac.uk/ > > -- > Paul Collinson ===== Dr. M A Al-Jubouri Consultant Chemical Pathologist ________________________________________________________________________ Want to chat instantly with your online friends? Get the FREE Yahoo! Messenger http://uk.messenger.yahoo.com/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/