The reference to this formula is "Bhagat, Garcia, Fletcher, Beilby. Calculated vs measured plasma osmolalities revisited. ClinChem: 1984; 1703 - 1705. We used the aformentioned osmol gap to estimate alcohol until we could meaure ethanol quickly and easily. Its good to measure rather than fudge, even if the fudge is fairly good! Paul Robinson Royal Berkshire Hospital Reading -----Original Message----- From: John Thompson To: [log in to unmask] Sent: 06/06/2003 12:00 Subject: Re: Use of osmolar gap to "estimate" blood alcohol Many years ago, the following formula was published. I think it was in the Annals. Sorry, don't have the reference. 1.89 [Na] + 1.38 [K] + 1.03 [UREA] + 1.08 [GLUCOSE] + 7.45 John Thompson DPOWH Grimsby UK -----Original Message----- From: David Brown [SMTP:[log in to unmask]] Sent: 06 June 2003 11:53 To: [log in to unmask] Subject: Use of osmolar gap to "estimate" blood alcohol I previously asked if there was a standard reference method for calculating osmolarityand of the 2 who gave replies (JK --2 X (Na + K) + Gluc +Urea and RGZ--(2 X Na)+Gluc +Urea) there would be an approximate difference of at least 2 X K, ie. 8 mmol. Any more formula users out there?. I used the Sigma blood alcohol method on our "acute lab analyser" for many years it was cheap and easy to run. David Brown __________________________________________________ Yahoo! Plus - For a better Internet experience http://uk.promotions.yahoo.com/yplus/yoffer.html ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/