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The reference to this formula is "Bhagat, Garcia, Fletcher, Beilby.
Calculated vs measured plasma osmolalities revisited. ClinChem: 1984; 1703 -
1705. We used the aformentioned osmol gap to estimate alcohol until we could
meaure ethanol quickly and easily. Its good to measure rather than fudge,
even if the fudge is fairly good!

Paul Robinson
Royal Berkshire Hospital
Reading

-----Original Message-----
From: John Thompson
To: [log in to unmask]
Sent: 06/06/2003 12:00
Subject: Re: Use of osmolar gap to "estimate" blood alcohol

Many years ago, the following formula was published. I think it was in
the
Annals. Sorry, don't have the reference.

1.89 [Na]  + 1.38 [K]  +  1.03 [UREA]  + 1.08 [GLUCOSE]  +  7.45

John Thompson
DPOWH
Grimsby
UK

        -----Original Message-----
        From:   David Brown [SMTP:[log in to unmask]]
        Sent:   06 June 2003 11:53
        To:     [log in to unmask]
        Subject:        Use of osmolar gap to "estimate" blood alcohol

        I previously asked if there was a standard reference
        method for calculating osmolarityand of the 2 who gave
        replies (JK --2 X (Na + K) + Gluc +Urea and RGZ--(2 X
        Na)+Gluc +Urea) there would be an approximate
        difference of at least 2 X K, ie. 8 mmol.
        Any more formula users out there?. I used the Sigma
        blood alcohol method on our "acute lab analyser" for
        many years it was cheap and easy to run.

        David Brown


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