Beningn Idiopathic hyperphosphatasaemia of infancy - well recognised
phenomenon.
See Abassi et al. Clin.Paed 1984;23:336
Benign elevation of AlkP: Transient and persistent variety.
and Arthur et al. Arch.Dis.Childhood 1984;59:996
Transient hyperphosphatasaemia
to give a couple of references.
-----Original Message-----
From: [log in to unmask] [mailto:[log in to unmask]]
Sent: 02 May 2003 16:10
To: [log in to unmask]
Subject: Raised Alkaline phosphatase in 18 month old
An 18 month year old presented to Paeds as "unwell". An Alk Phos of 5797 U/L
and an Iron of 3 umol/l were found as the only abnormalities (Normal LFTs,
U/E, calcium, PO4). I think the child was born in Nigeria, and thought the
Alk Phos represented Vit D deficiency, but the 25 OH Vit D was normal. The
child was started on Iron, and 7 weeks later the Iron is 15 umol/l, and the
Alk Phos is 368U/L, which would be considered normal for the age. Any ideas
as to why the Alk Phos was so elevated 7 weeks previously, resolved so
quickly, and the only interventional medication was Iron?
____________________________________________________________
Dr. Helen Grimes, Dept. of Clinical Biochemistry, UCH, Galway, Ireland
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