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Is everyone convinced that HRT is such a bad thing?  Admittedly the
short-term prothrombotic effect in patients with CHD is adverse, but the
curves in HERS do tend to converge after a few years.  Gallstones are a
nuisance.  The million women study was not randomised and I'd be surprised
if HRT can cause cancer so quickly (i.e. was it there before in a denser
breast).  The lipid results are still appealing, and the QALY score for some
(non-CHD) patients might be quite good.  Are the alternatives for
osteoporosis as palatable and effective?  Or are we now against HRT?

Andrew
-----Original Message-----
From: Mainwaring-Burton Richard (RGZ)
[mailto:[log in to unmask]]
Sent: 04 December 2003 11:17
To: [log in to unmask]
Subject: Re: CMO Advice on HRT in the over 50s with osteoporosis

It is a bit like the reccomendation "Employ a teenager NOW while he still
knows everything"

with best wishes

Richard

Richard Mainwaring-Burton
Consultant Biochemist
Queen Mary's Hospital
Sidcup, Kent
DA14 6LT
020-8308-3084


-----Original Message-----
From: ablumsohn [mailto:[log in to unmask]]
Sent: 04 December 2003 08:27
To: [log in to unmask]
Subject: Re: CMO Advice on HRT in the over 50s with osteoporosis


As they say:

"Use a new drug while it's still effective"

Aubrey


GMA> This document became available at 15:00
GMA> today relating to the use of HRT in women over 50
GMA> years old.

GMA> Malcolm Gray

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