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Nikki,
  I read your post with interest.  What type of cushion is she sitting on?
Is it fluid (Jay2 type) or air (Roho type)?  The air cushions don't offer
the most optimal positioning, but they are the best for overall pressure
relief.  Since the sore is over her ischial tuberosity, I would guess that
seated pressures are more the problem rather than lying ones.  If the tilt
is adequate with the chair (somewhere around 60 degrees), the pressures over
the tuberosities should approach zero in full tilt.  If this is the case,
then more frequent and longer duration pressure relief may be necessary.
  Unfortunately, many sores are stubborn and unrelenting enough not to
tolerate any pressure whatsoever.  In these cases, the patient has only two
choices: stay off of it until it heals (months and months), or opt for skin
flap surgery.  If you exhaust all options, I'd ask her physician to counsel
her to seriously consider the surgery.
  Depending on the person's upper extremity function, many have found at
least some independence in mobility pushing a prone cart.  It's not the best
means of mobility, but it's better than nothing.
  There are also many new advances in wound care available.  Each option has
varying levels of success with individual patients.  There is the medication
Regranex, which works well when there is 90% or more granulation tissue in
the wound (although it is expensive).  Other options include dressings
attached to a vacuum machine (negative pressure therapy), dressings with
heating pads (thermotherapy), electrical stimulation (galvanic and
microstim), pulsed lavage (alternative to whirlpools), etc, etc.
  I hope you find what works for the benefit of your client.  Pressure sores
are probably one the most tenacious and frustrating problems we deal with in
our profession.

Warm Regards,
Geoff Mosley, PT, NCS
MRC
Mount Vernon, MO