Dear fellow SPM users, If I want to coregister a neurological image (say an EPI) to a radiological image (say a T1), can I just flip the latter by zooming in x by -1 and reorienting? (Ie, will that method of flipping be seen by the coregistration program?) Also, is the coregistration algorithm symmetric in its action, ie is the linear transform that coregisters A to B the inverse of that that coregisters B to A? Stephen Fromm NIDCD/NIH, USA