On Thu, 14 Feb 2002, Qingyan Guan wrote: > Sorry, I forgot to give the websit address. It is: > http://staff.washington.edu/qguan I ran siena ellison.baseline.0 ellison.followup.12 -2 (-2 because there is low grey/white contrast) and it worked fine, showing a large amount of atrophy. it may be that you need to grab either the flirt or the fast patches from http://www.fmrib.ox.ac.uk/fsldownloads/patches/1.3/ Thanks, Steve.