Hi. Sure - you can try this - though I have no idea whether there will be sufficient information in this cut-down ROI of the eye to robustly find motion parameters. Yes - you can easily use avwroi - you want to specify a 3D ROI which will turn a 3D image into a 3D ROI or a 4D image into a cut-down 4D image. So use: avwroi <input> <output> <xmin> <xsize> <ymin> <ysize> <zmin> <zsize> Thanks, Steve. On Thu, 28 Nov 2002, Arun Bokde wrote: > Hello FSLers, > > A recent paper (Tregellas J et al, HBM, vol 17: 237-243) shows that a > measure of eye movement can be obtained by using the standard EPI > sequences. I am interested in trying it out using FLIRT, as the method > described basically is a rigid body registration process on the time > series of each eye. Is there any reason that FLIRT would have problems > with a time series file that has perhaps 10 x 10 voxels per slice and > 4-5 slices ? Is there a program that could produce a 4D avw file from > another 4D avw file based on an ROI ? I was looking at avwroi but the > help info is not very clear to me. > > TIA > > Cheers, Arun > Stephen M. Smith Head of Image Analysis, FMRIB Oxford University Centre for Functional MRI of the Brain John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve