The latest release of the FMRIB Software Library (3.0, October 2002) is now available for downloading from http://www.fmrib.ox.ac.uk/fsl There are many additions since the last release (June 2001), the main ones being: * FEAT v5: - Bayesian multi-subject FMRI analysis: General GLM for higher-level analysis (e.g. analysis across sessions or across subjects; paired t-tests, three-level groupings etc): FLAME (FMRIB's Local Analysis of Mixed Effects). FLAME uses very sophisticated methods for modelling and estimating the random-effects component of the measured inter-session mixed-effects variance, using MCMC to get an accurate estimation of the true random-effects variance and degrees of freedom at each voxel. * MELODIC v2: - Probabilistic ICA (PICA) for FMRI. By adding a Gaussian noise model to the ICA model, and automatically estimating the dimensionality (the number of non-Gaussian components), it is now possible to create meaningful Z-statistic maps for each spatial component, allowing inference ("thresholding"). - Inference on the Z-statistic images is carried out with a Gaussian/Gamma mixture model (fitted using EM), fitting central noise and activation classes; thus alternative hypothesis testing is used. * Interoperation with FreeSurfer and AFNI For a more complete list see http://www.fmrib.ox.ac.uk/fsl Thanks for your interest, enjoy! the FMRIB Analysis Group.