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Julian

The half-life of Co-Hb is as follows:

      4 - 6 hours when the patient is on room
      40 - 80 minutes on 100% oxygen
      15 - 30 minutes on hyperbaric oxygen.

Reference:
1.Ernst A, Zibrak JD. Carbon monoxide poisoning. N Engl J Med 1998;339:1603-1608. 

PD Rambau
Consultant Chemical Pathologist
IPS,South Africa
----- Original Message -----
From: Julian Barth <[log in to unmask]>
Date:         Tue, 13 Aug 2002 09:33:54 -0000
To: [log in to unmask]
Subject: CO-haemoglobin: help please


> Does anyone have information of CO-Hb kinetics. I have been
> specifically asked about the decay of CO-Hb after removal from the
> source of the gas but within a normal atmospheric O2 environment.
> Is there any information about the rate of loss of tissue CO after the
> CO-Hb has returned to a "normal" value and how it is assessed.
> 
> Many thanks
> Julian
> ___________________________________________________
> 
> Julian H Barth
> Department of Clinical Biochemistry & Immunology
> Leeds Teaching Hospitals NHS Trust
> Leeds General Infirmary
> Great George Street
> Leeds LS1 3EX
> tel 0113-392-3416
> fax 0113-392-5174
> ___________________________________________________
> 
> ------ACB discussion List Information--------
> This is an open discussion list for the academic and clinical
> community working in clinical biochemistry.
> Please note, archived messages are public and can be viewed
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 Tue, 13 Aug 2002 05:21:54 -0500
Subject: Re: CO-haemoglobin: help please
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Julian

The half-life of Co-Hb is as follows:

      4 - 6 hours when the patient is on room
      40 - 80 minutes on 100% oxygen
      15 - 30 minutes on hyperbaric oxygen.

Reference:
1.Ernst A, Zibrak JD. Carbon monoxide poisoning. N Engl J Med 1998;339:1603-1608. 

PD Rambau
Consultant Chemical Pathologist
IPS,South Africa
----- Original Message -----
From: Julian Barth <[log in to unmask]>
Date:         Tue, 13 Aug 2002 09:33:54 -0000
To: [log in to unmask]
Subject: CO-haemoglobin: help please


> Does anyone have information of CO-Hb kinetics. I have been
> specifically asked about the decay of CO-Hb after removal from the
> source of the gas but within a normal atmospheric O2 environment.
> Is there any information about the rate of loss of tissue CO after the
> CO-Hb has returned to a "normal" value and how it is assessed.
> 
> Many thanks
> Julian
> ___________________________________________________
> 
> Julian H Barth
> Department of Clinical Biochemistry & Immunology
> Leeds Teaching Hospitals NHS Trust
> Leeds General Infirmary
> Great George Street
> Leeds LS1 3EX
> tel 0113-392-3416
> fax 0113-392-5174
> ___________________________________________________
> 
> ------ACB discussion List Information--------
> This is an open discussion list for the academic and clinical
> community working in clinical biochemistry.
> Please note, archived messages are public and can be viewed
> via the internet. Views expressed are those of the individual an´ñ¿¿“ Ë

------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.

ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/