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Just a brief word of warning if you intend to use this test in patients who have had any surgical intervention. Protein S100 is found in some extra-CNS sites - including subcutaneous fat. During surgery, traumatic damage to this fat causes a rapid release of the protein into the systemic circulation. This may (and has been) be misenterpreted as CNS damage. Althought the protein is cleared renally, we have not found any significant influence of renal impairment on plasma concentrations of S100. I think you'll find that the test is carried out at the Institute of Neurology in London. Andrew Trull, PhD Clinical Scientist Grade C Head of Clinical Pharmacology Department of Pathology Papworth Hospital Papworth Everard Cambridge CB3 8RE Tel.: 01480-830541 (x4301) FAX: 01480-364777 On Fri, 21 Dec 2001, Sharpe, Peter Dr wrote: > Dear All, > > Does anyone know where I can get S100 measured? AssayFinder is of no help! > > Peter Sharpe > Craigavon Area Hospital >