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This looks exciting but BEWARE - the figures after the brackets in the original paper are powers and not integers, so conversion becomes a little more hairy ! With best wishes Richard -----Original Message----- From: Fisher, Roy - RCHT [mailto:[log in to unmask]] Sent: Wednesday, January 09, 2002 10:34 To: [log in to unmask] Subject: Re: Creatinine clearance test using 6 hours timed urine collectio n Mohammad In conjunction with our renal physicians we have recently started to provide calculated creatinine clearances using the Cockcroft-Gault formula, with view to abandoning conventional creatinine clearances. They have also asked us to look at at another equation that is claimed to be a more accurate estimate of GFR without requiring the patient's weight. However, as you can see it's a more complex calculation that uses non-SI units and we have not got round to setting up the algorithm yet. There are also method related factors that need to be considered as seen from comparative laboratory data on the UK Renal Registry. GFR = 170 x (plasma creat mg/ml)-0.999 x (age)-0.176 x (0.762 if patient is female) x (1.180 if patient is black) x (serum urea mg/dl)-0.17 x (albumin g/dl)+ 0.318 Levey AS et al Ann Intern Med 1999; 130: 461-470 The paper is available on line at http://www.acponline.org Kind regards Roy Fisher Royal Cornwall Hospital Truro -----Original Message----- From: Mohammad Al-Jubouri [mailto:[log in to unmask]] Sent: Tuesday, January 08, 2002 14:51 To: [log in to unmask] Subject: Creatinine clearance test using 6 hours timed urine collection Dear Colleagues A care of the elderly physician asked whether we could shorten the time of collection for CCT for his elderly demented clients who wants to start them on nephrotoxic drugs and also to help with calculation of the dose. Given that CCT is only a rough estimate of GFR, would list members make a concession for such a request? Has plasma cystatin C found its way to routine clinical use? Thanks Mohammad ===== Dr. M A Al-Jubouri Consultant Chemical Pathologist __________________________________________________ Do You Yahoo!? Everything you'll ever need on one web page from News and Sport to Email and Music Charts http://uk.my.yahoo.com