Helen
It may be of interest to look at the American Society of Clinical Oncolgy guidelines which are evidence based guidelines which are updated annually.
Breast cancer: http://www.asco.org/prof/pp/html/guide/brstint/m_brstint.htm <http://www.asco.org/prof/pp/html/guide/brstint/m_brstint.htm>
Colorectal cancer: http://www.asco.org/prof/pp/html/guide/color/m_colorguide.htm <http://www.asco.org/prof/pp/html/guide/color/m_colorguide.htm>
Sandra Rainbow
-----Original Message-----
From: p=NHS NATIONAL INT;a=NHS;c=GB;dda:RFC-822=ACB-CLIN-CHEM-GEN(a)JISCMAIL.AC.UK;
Sent: 15 April 2002 14:17
To: p=NHS NATIONAL INT;a=NHS;c=GB;dda:RFC-822=ACB-CLIN-CHEM-GEN(a)JISCMAIL.AC.UK;
Subject: Frequency of tumour marker measurements
Dear All,
I've been asked to suggest minimum frequencies for assaying various
endocrine and tumour markers in our department. I have realised that
although I have been using as my rule of thumb, that tumour markers should
not be assayed more frequently than once for each of their respective half
lives, I have no evidence to back up this feeling.
Can anyone point me in the direction of some suggestions/guidelines for how
frequently one should measure: AFP, CEA, CA125,CA153, CA199, PSA and HCG ?
I'm thinking in terms of monitoring progression, not diagnostic uses.
Thanks in anticipation of help
Helen Smith
Clinical Biochemistry
The Royal Free Hospital
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