 |
 |
Trevor I'm not quite sure what you are saying here. Are you saying that it is worthwhile measuring urine myoglobin since CK will not always be raised in myoglobinuria? In the abstract you quote the myoglobin method is not given but I suspect it to be a non-specific and the timing of the samples may also be important. I agree with Gerald. There is no evidence that the measurement of urine myoglobin is helpful in trauma care. Douglas Thompson Leeds General Infirmary > There are several questions here. > > 1) Does raised CK tell you that there is myoglobinuria? > 2) Can myoglobinuria exist without raised CK? > 3) Does treatment of myoglobinuria benefit the patient? > > The answer to 1) is no - or at least not in all situations. See, for > example http://www.aaos.org/wordhtml/anmeet92/scipro/ppr313.htm I do > not know the answer to 2) and would be interested in the evidence. I > believe that the evidence for benefit to the patient of active > treatment is limited but generally medical wisdom is that diuresis is > warranted. > > Trevor Tickner, > Norwich > > > -----Original Message----- > > From: Gerald. Maguire [SMTP:[log in to unmask]] > > Sent: 09 April 2002 15:33 > > To: [log in to unmask] > > Subject: Re: Heavy myoglobinuria and urine colour > > > > What does the measurement of urine myoglobin tell you that the > > measurement of serum CK does not? After consultation with the > > critical care teams (ITU and neuro), we stopped measuring urine > > myoglobin about 18 months ago and nobody misses it. > > > > Gerald A Maguire > > Dept of Clinical Biochemistry and Clinical Immunology > > Addenbrooke's Hospital > > Cambridge > > CB2 2QR > > UK > > Tel 44 (0) 1223 217159 > > fax 44 (0) 1223 217794 Dr Douglas Thompson Department of Clinical Biochemistry and Immunology Leeds Teaching Hospitals NHS Trust The General Infirmary Leeds, LS1 3EX Tel: 0113 3926503 Fax: 0113 2335672 ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/