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We recently had a case of significant discrepancies between a glucose meter and the lab method. The meter was a Roche Accutrend Inform (glucose dehydrogenase) and the lab method is glucose oxidase. The discrepancy occurred shortly after tha patient had been given IV human immunoglobulin - "Octagam". Octagam contains 40% maltose, and the native preparation gives a very high reading with the glucose meter but not with the glucose oxidase method. How is maltose removed from blood when given IV? I wanted to confirm this finding before reporting to the MDA by looking at a few more patients, but such is the rampant beaurocracy of the NHS that I am required to submit a full research proposal to be allowed to take three blood samples. I thought it would be easier to try the mailbase instead on the understanding that, in publishing circles, if three other people think so it becomes a well known fact. Incidentally, I recently heard from Roche that the basis of Icodextrin interference is that it is metabolised to maltose, maltotriose and maltotetraose. Doug Hirst Biochemistry Dept Bradford Royal Infirmary ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/