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I would have thought that the potential risk of a positive opiates test due to cross-reactivity of the test with, for example, OTC codeine (as in solpadeine etc) would be of serious concern if the test result is going to be a direct determinant of subsequent treatment. With regard to the cut-off concentration, what do the respective manufacturers calibrate their devices against? Regards, Simon. Dr Simon Walker Medscreen Ltd, Harbour Quay, Prestons Road, London E14 9PH. Tel: 020 7712 8000 Fax: 020 7712 8001 Fax to desk: 0870 400 5757 email: [log in to unmask] > -----Original Message----- > From: Evans, Francis - RCHT [SMTP:[log in to unmask]] > Sent: Wednesday, July 10, 2002 9:55 AM > To: [log in to unmask] > Subject: DRUGS OF ABUSE POCT in pregnancy > > OPIATE 'DIPSTICKS' for screening Pregnant patients with an > unreliable > history. > > Our drug liaison midwife and obstetric consultants are insisting on using > 'Surestep' for drugs of abuse; mainly for Opiates in order to ensure that > Naloxone is not given to mothers who are suspected of, but deny, the use > of > Opiates. > Our Trust POCT working group is arranging guidelines, operating procedures > and QC and EQA schemes. > > Our own DOA screening is done on our Roche Integras but the cut off values > are different. > > Roche Pos / Neg cut-off is 300 and Surestep Cut-off is 1000 > > Can a cut-off of 1000 be considered suitable for contra-indication of > Naloxone treatment or are they wasting their time ? > > Does anyone have experience of DOA screening in pregnancy as a Point of > Care > test. > > Francis Evans ( [log in to unmask] ) > Clinical Chemistry > Royal Cornwall Hospitals Trust > Truro > Cornwall > > ________________________________________________________________________ > This e-mail has been scanned for all viruses on behalf of Medscreen Ltd. > Email received by Medscreen may be archived and monitored. > ________________________________________________________________________ > ________________________________________________________________________ This e-mail has been scanned for all viruses on behalf of Medscreen Ltd. Email sent by Medscreen may be archived and monitored.