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Many thanks for all the replies. I must plead ignorance with respect to SAA - I was informed that SAA won't rule in or out amyloidosis as its behaviour is very similar to CRP' and the endocrine SpR was happy to accept this and do a rectal biopsy instead. Pat Dr. Pat Twomey, Department of Clinical Biochemistry, Royal Infirmary, Edinburgh EH3 9YW. tel: 0131-5362704 fax: 0131-5362758 ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/