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The use of high dose diazepam for the treatment of chloroquine poisoning is quoted by Toxbase. "Diazepam (2 mg/kg body weight intravenously over 30 min) may have a protective effect in severe poisoning but should probably only be used in combination with assisted ventilation." I understand that it, "protects the heart" from the toxic effects of the drug.

My question is could it have a similar effect in tricyclic overdose? 

Regards

Ray McGlone
A&E Lancaster