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In a message dated 8/17/01 6:01:31 PM Pacific Daylight Time, [log in to unmask] writes: > And Stephen Senn has argued in an eLetter to the BMJ that equipoise is not > Hello: I know that the discussion about randomized and non-randomized trials and clinical equipoise was awhile ago. I apologize for not keeping up with my email better. But I think these two references are critical reading regarding the topic of clinical equipoise: Sackett DL. Uncertainty about clinical equipoise. There is another exchange on equipoise and uncertainty. BMJ. 2001 Mar 31;322(7289):795-6. Sackett DL. Equipoise, a term whose time (if it ever came) has surely gone. CMAJ. 2000 Oct 3;163(7):835-6. Cheers and Best Wishes, Brian .................................... Brian Budenholzer, MD Director, Clinical Enhancement & Development ACN18 Group Health Cooperative; Network Services Division PO Box 204 Spokane, WA 99210-0204 USA [log in to unmask] 509/ 838-9100 X 7393 fax: 509/ 458-0368 ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,