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Dear all This has been puzzling me for a while: Assuming a block size of 6 to randomise equivalent numbers to three different treatment groups (A,B,C), how do I find out what the total different number of combinations of AABBCC etc are, short of working it out by hand? Straight permutation (6x5x4x3x2x1) does not seem to give the answer as I can only work out 40 odd different combinations and the permutation suggests 720. Is there another formula to use? Any help would be gratefully received. Andrew Jull Clinical Nurse Consultant Auckland Hospital NEW ZEALAND NB my email address has changed to [log in to unmask] Please update your address book.