I am also very interested in this topic and appreciate the tip from Philip Hall. Two other places to start: 1) the Society of Medical Decision Making - they have a journal. I recall when I was looking at some of their earlier issues, there were some articles in this area. 2) this also relates to the field of medical epistemology and medical cognition, in particular, how clinicians learn how to act without perfect certainty, something that at its base is human, but also is particularly problematic in the medical field given our societal values about health and perfection. Three articles (among many others I'm certain) I've found interesting in this area are Malterud K, "The legiimacy of clinical knowledge: towards a medical epistemology embracing the art of medicine" Theoretical Medicine 1995;16:183-98 Tonelli M, "The philosophical limits of evidence-based medicine" Academic Medicine 1998;73:1234-40 Schmidt HG et.al., "A cognitive perspective on medical expertise: theory and implications" Academic Medicine 1990;65:611-21 Please summarize your findings for the list and thanks for your question - wish I'd asked it! Ken Yew NH Jacksonville Department of Family Practice (904) 777-7963 dsn 942 -----Original Message----- From: Andy Smith [mailto:[log in to unmask]] Sent: Saturday, August 11, 2001 8:47 AM To: [log in to unmask] Subject: uncertainty in evidence-based medicine I'm interested in exploring uncertainty in EBM - how it arises (different causes) and what doctors and their patients do when there is no evidence. Any ideas?