 |
 |
Medline may not yet be up to speed but you can find it on embase Shane ----- Original Message ----- From: John Chambers <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, 11 June 2001 6:14 Subject: Re: Prophylactic metaclopramide > Unfortunately the Australasian journal (Emergency Medicine) is not on > medline although a decision is pending! > > The role of prophylactic anti-emetic therapy in emergency department > patients receiving intravenous morphine for musculoskeletal trauma > Emergency Medicine(1999) 11, 240-243 > Lambie, Chambers and Herbison > Dunedin Hospital, Dunedin NZ > > A randomised double blind controlled trial 214 patients comparing > metoclopramide with placebo > 3.7% vomited (1.9% in the control group and 5.4% in the group receiving > metoclopramide) > Hardly any vomiters in this selected group > mean age of vomiters 78.5 > mean age of non vomiters 46.0 This was highly significant p=0.0009 > > Few vomited and they were almost all old! > We resticted to musculoskeletal trauma in an attempt to remove other > clinical causes of vomiting apart from the opioid > took 8 months to do this small study > it should be possible to set up multicente comtrol trials to answer > these simple questions in one weekend with thousands of patients! > > I use ondansetron as a prophylactic antiemetic when it really matters > JohnC > ###################################################################### > > Attention: > This e-mail is privileged and confidential. If you are not the > intended recipient please delete the message and notify the sender. > Any views or opinions presented are solely those of the author. > > ######################################################################