Well this rather led me to that conclusion: >Besides there's nothing like a thio GA for depressing your resps, > BP and GCS! (thio is after all a barbiturate,isn't it?). Respiratory depression will lead to poor oxygen delivery. I did not want people to go away with the idea that GA was not a good idea in seizure control; it is still the treatment of choice. However, it is important to distinguish between being anaesthetised and having your cerebral seizure activity terminated. You can be completely immobile as a result of muscle relaxant drugs and yet still have massive aberrant cerebral electrical activity. Best wishes, Rowley Cottingham [log in to unmask]