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You should find some good references in the Bandolier's site (Diagnostic testing emerging from the gloom, Tuberculosis diagnosis, etc.). A rare metanalysis on diagnostic tests for UTIs is by Gorelick et al in Pediatrics 104 (5) page ?, 1999. Ebell et al use an LR-based clinical prediction rule for Strep Throat (JAMA 284,2912,2000). More examples in Black et al Diagnostic Strategies for common medical problems 2nd Ed 1999, ACP. A review on the physicians' testing practices in JAMA 1998, 280, 2020. Hope it helps. I'm strongly interested on this subject, too. Did you find anything else? Giuseppe At 16.22 23/01/01 +1300, you wrote: >I am trying to put together some reading for an EBP paper. I have found very >few papers investigating or empirically demonstrating the impact of the >factors influencing validity in diagnostic studies outlined in the JAMA >series and Sackett et al's book. > >Does anybody have some good references or a list of such? > >Andrew Jull >Clinical Nurse Consultant >Auckland Hospital >NEW ZEALAND Dr. Giuseppe Giocoli Gruppo di Lavoro EBM Associazione Microbiologi Clinici Italiani Via Sarca, 19 25015 DESENZANO d/G (BS) Italia