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> Is there any utility to apply the *sn3d data to the normalized image to get > the image in the original space? Because SPM's segmentation will be done in > the spatial normalized space, what if we want to measure the volume > combinations in the original space? Thanks a lot. You could try messing around with the Deformations Toolbox. See the following links for some ideas about how to generate inverse deformation fields. http://www.jiscmail.ac.uk/cgi-bin/wa.exe?A2=ind0112&L=spm&P=R18565 http://www.jiscmail.ac.uk/cgi-bin/wa.exe?A2=ind0108&L=spm&P=R12951 Once you have the inverted field, then you can apply it to your spatially normalised image. Best regards, -John -- Dr John Ashburner. Functional Imaging Lab., 12 Queen Square, London WC1N 3BG, UK. tel: +44 (0)20 78337491 or +44 (0)20 78373611 x4381 fax: +44 (0)20 78131420 http://www.fil.ion.ucl.ac.uk/~john