Hello Mark, > dI am trying to find the center of mass for evaluation of both the size of > the voxel and also the volume of the voxel itself. Does anyone know of a > way to do this using spm or must you use matlab to do so? if so what is the > best way at going about this. > thankyou for your help > mark I really wouldn't know if SPM supports this. When automated the normalisation of PET images, I also had to set the origin in the .mat-files as the normalisation routines are very sensitive to translations in the starting transformation. Attached is a try-out program I used to compute the centre of mass in a volume. It is very general, but I think it can be embedded very easily if you are willing to write your own matlab functions. Hope this helps, Alle Meije Wink -- Alle Meije Wink Institute for Mathematics and Computing Science, room 105 University of Groningen P.O. Box 800 9700 AV Groningen Telephone +31 50 363 71 27 The Netherlands Fax: +31 20 875 48 00 E-mail: [log in to unmask] WWW: http://www.cs.rug.nl/~wink " I guess it comes down to a simple choice, really. Get busy living, or get busy dying. " (Andy Dufresne in The Shawshank Redemption)