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Dear Andreas,

> is it possible to define a region of interest in SPM to count activated
> voxels within this region?

You can use the small volume correction in SPM99 to search a specified
spherical or cubic region around a coordinate or coordinates of interest for
activated voxels. For more complicated ROI shapes the small volume
correction will also search for activation in a predefined image volume, but
this ROI image would need to be created outside SPM (e.g. with MRIcro).

Best wishes,

Geraint

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