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I believe the shape of the HRF was empirically derived based on the work of Zarahn Zarahn, E., G. Aguirre, and M. D'Esposito, A trial-based experimental design for fMRI. Neuroimage, 1997. 6(2): p. 122-38. Best wishes, Sterling C. Johnson, Ph.D. Neuropsychology Barrow Neurological Institute 222 W. Thomas Rd. Ste 315 Phoenix AZ 85013 ph: 602-406-3671 fx: 602-406-6115 email [log in to unmask] > -----Original Message----- > From: Dr Afraim Haddadi [mailto:[log in to unmask]] > Sent: Wednesday, February 07, 2001 11:39 AM > To: [log in to unmask] > Subject: SPM HRF Reference > > > Dear all, > > Can anyone provide me with a literature reference for > the default canonical HRF shape, assumed by spm_hrf? > > Much appreciated, > > Afraim > > > ---------- > Dr A Salek-Haddadi > Clinical Research Fellow > Institute of Neurology >