Dear all I was wondering if anyone had ideas about temporal filtering for phamacological fmri. Due to the nature of the exp , we only have one off and one on condition. The off condition consists of 12 continuos 5 minute scans. This is followed by injection of a phamacological agent (on condition ) and then a futher 18 five minute scans are taken. Because this exp is so long and the nature of the paridgm being a long off and on condition, should i be using a filter twice as long as the exp time? any suggestions will be gratefully received Yas Yasmene Shah Magnetic Resonance Centre University of Nottingham NG7 2RD Tel. no. 44 (0)115 915 5151 ext 18286/14751